{"id":38,"date":"2023-12-27T11:00:04","date_gmt":"2023-12-27T10:00:04","guid":{"rendered":"https:\/\/physicsworld.com\/?p=111911"},"modified":"2023-12-27T11:00:04","modified_gmt":"2023-12-27T10:00:04","slug":"medical-physics-and-biotechnology-highlights-of-2023","status":"publish","type":"post","link":"https:\/\/hadamard.com\/c\/medical-physics-and-biotechnology-highlights-of-2023\/","title":{"rendered":"Medical physics and biotechnology: highlights of 2023"},"content":{"rendered":"<p>This year, the <em>Physics World<\/em> team selected a medical innovation as the <a href=\"https:\/\/physicsworld.com\/a\/brain-computer-interface-that-allowed-a-paralysed-man-to-walk-is-the-physics-world-2023-breakthrough-of-the-year\/\">Breakthrough of the Year<\/a>: the development of a digital bridge that restores communication between the brain and spinal cord, enabling a man with paralysis to stand and walk naturally. We also reported on several other neural engineering advances, including a neuroprosthesis that <a href=\"https:\/\/physicsworld.com\/a\/high-performance-brain-implants-restore-communication-to-those-who-cannot-speak\/\">restores communication to those who cannot speak<\/a> and an award-winning implant that could help <a href=\"https:\/\/physicsworld.com\/a\/machine-learning-meets-nanotechnology-award-winning-implant-regulates-blood-pressure\/\">regulate blood pressure<\/a> in people with spinal-cord injuries.<\/p>\n<p>n<\/p>\n<p>And that\u2019s just one example of the impact of physics-related research on the healthcare sector. In 2023, we wrote about a host of medical physics and biotechnology advances, from <a href=\"https:\/\/physicsworld.com\/a\/photon-counting-detectors-lower-contrast-related-risks-in-ct-angiography\/\">photon-counting detectors<\/a> that produce high-quality images with less contrast media to hydrogels that help <a href=\"https:\/\/physicsworld.com\/a\/hydrogel-helps-grow-new-tissue-in-areas-of-brain-damage\/\">grow new brain tissue<\/a> to <a href=\"https:\/\/physicsworld.com\/a\/shoot-through-proton-flash-a-robust-approach-to-brain-tumour-treatment\/\">shoot-through FLASH proton therapy<\/a>. Here are a few more highlights that caught our eye.<\/p>\n<p>n<\/p>\n<h3><strong>Novel takes on nuclear medicine <\/strong><\/h3>\n<p>n<\/p>\n<p>Among the many developments in positron emission tomography (PET) technology announced this year, a research team headed up at Memorial Sloan Kettering Cancer Center and Complutense University of Madrid devised a novel image reconstruction method that enables <a href=\"https:\/\/physicsworld.com\/a\/multiplexed-pet-can-image-two-radiotracers-in-a-single-scan\/\"><em>in vivo<\/em> imaging of two different PET tracers simultaneously<\/a>. This \u201cmultiplexed PET\u201d technique, which increases the amount of information attainable during a single scan, can be implemented on preclinical or clinical PET systems without having to modify the hardware or image acquisition software.<\/p>\n<p>n<\/p>\n<figure class=\"size-full wp-image-109060\" id=\"attachment_109060\"><a data-featherlight=\"image\" title=\"Click to open image in popup\" href=\"https:\/\/physicsworld.com\/wp-content\/uploads\/2023\/07\/mPET-fig1.jpg\"><img decoding=\"async\" loading=\"lazy\" class=\"size-full wp-image-109060\" src=\"https:\/\/physicsworld.com\/wp-content\/uploads\/2023\/07\/mPET-fig1.jpg\" alt=\"Overview of multiplexed PET\" width=\"1200\" height=\"675\" srcset=\"https:\/\/physicsworld.com\/wp-content\/uploads\/2023\/07\/mPET-fig1.jpg 1200w, https:\/\/physicsworld.com\/wp-content\/uploads\/2023\/07\/mPET-fig1-211x119.jpg 211w, https:\/\/physicsworld.com\/wp-content\/uploads\/2023\/07\/mPET-fig1-1024x576.jpg 1024w, https:\/\/physicsworld.com\/wp-content\/uploads\/2023\/07\/mPET-fig1-317x178.jpg 317w, https:\/\/physicsworld.com\/wp-content\/uploads\/2023\/07\/mPET-fig1-768x432.jpg 768w, https:\/\/physicsworld.com\/wp-content\/uploads\/2023\/07\/mPET-fig1-711x400.jpg 711w, https:\/\/physicsworld.com\/wp-content\/uploads\/2023\/07\/mPET-fig1-732x412.jpg 732w, https:\/\/physicsworld.com\/wp-content\/uploads\/2023\/07\/mPET-fig1-720x405.jpg 720w, https:\/\/physicsworld.com\/wp-content\/uploads\/2023\/07\/mPET-fig1-635x357.jpg 635w, https:\/\/physicsworld.com\/wp-content\/uploads\/2023\/07\/mPET-fig1-350x197.jpg 350w, https:\/\/physicsworld.com\/wp-content\/uploads\/2023\/07\/mPET-fig1-257x145.jpg 257w, https:\/\/physicsworld.com\/wp-content\/uploads\/2023\/07\/mPET-fig1-300x169.jpg 300w, https:\/\/physicsworld.com\/wp-content\/uploads\/2023\/07\/mPET-fig1-160x90.jpg 160w, https:\/\/physicsworld.com\/wp-content\/uploads\/2023\/07\/mPET-fig1-128x72.jpg 128w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><\/a><script type=\"application\/json\">\"\\u003Cstrong\\u003EDual isotope imaging\\u003C\\\/strong\\u003E Overview of multiplexed PET using a pure positron emitter and a positron\\u2013gamma emitting radionuclide. (Courtesy: E C Pratt \\u003Cem\\u003Eet al Nat. Biomed. Eng\\u003C\\\/em\\u003E 10.1038\\\/s41551-023-01060-y 2023 Springer Nature)\"<\/script><figcaption class=\"gallery-item__caption\"><strong>Dual isotope imaging<\/strong> Overview of multiplexed PET using a pure positron emitter and a positron\u2013gamma emitting radionuclide. (Courtesy: E C Pratt <em>et al Nat. Biomed. Eng<\/em> 10.1038\/s41551-023-01060-y)<\/figcaption><\/figure>\n<p>n<\/p>\n<p>Aiming to meet the ever-increasing clinical demand for PET scans, researchers at Ghent University in Belgium are developing a <a href=\"https:\/\/physicsworld.com\/a\/walk-through-pet-scanner-made-for-high-throughput-imaging-at-lower-cost\/\">walk-through total-body PET scanner<\/a>. Their proposed upright imaging system, which looks a bit like an airport security scanner, is expected to be both cheaper and quicker to use than standard PET instruments.<\/p>\n<p>n<\/p>\n<p>And researchers at UC Davis used total-body PET to perform first-in-human <a href=\"https:\/\/physicsworld.com\/a\/total-body-pet-imaging-reveals-immune-response-in-covid-19-patients\/\">immunoPET imaging of T cell biodistribution<\/a> in three healthy individuals and five patients recovering from COVID-19. Quantification of immune cell distribution and kinetics in humans can shed light on how the immune system responds to viral infections, and help researchers develop new vaccines and improved treatments.<\/p>\n<p>n<\/p>\n<h3><strong>Radiotherapy for the future<\/strong><\/h3>\n<p>n<\/p>\n<p>The introduction of MR-guided radiotherapy, which uses MRI to visualize tumours and surrounding organs with high accuracy while the patient is on the treatment table, enables clinical advances such as real-time plan modification and imaging of moving tumours during treatment delivery. But integrated MR-linac systems hold potential to do a lot more.<\/p>\n<p>nn<\/p>\n<p>Researchers at the University Hospital of Zurich investigated an approach called <a href=\"https:\/\/physicsworld.com\/a\/adaptive-fractionation-pushes-the-boundaries-of-mr-guided-radiotherapy\/\">adaptive fractionation<\/a>, which exploits inter-fraction motion (rather than simply compensating for it) by adjusting the prescribed dose according to the distance between the tumour and organs-at-risk (OAR) on each day. In other words, a patient is prescribed a higher radiation dose on days when their tumour\u2013OAR separation is large and a lower dose on days when this separation is small.<\/p>\n<p>n<\/p>\n<p>Elsewhere, a team at the University of Toronto\u2019s Sunnybrook Health Sciences Centre studied the use of <a href=\"https:\/\/physicsworld.com\/a\/imaging-on-an-mr-linac-identifies-radiation-resistant-brain-tumours\/\">diffusion-weighted imaging (DWI) on an MR-linac<\/a> to improve treatment of the aggressive brain cancer glioblastoma. The idea here is to use DWI to identify regions of treatment-resistant tumour and deliver higher doses to these targets.<\/p>\n<p>n<\/p>\n<figure class=\"size-full\" id=\"attachment_105543\"><a data-featherlight=\"image\" title=\"Click to open image in popup\" href=\"https:\/\/physicsworld.com\/wp-content\/uploads\/2023\/01\/Upright-rt-featured.jpg\"><img decoding=\"async\" loading=\"lazy\" class=\"wp-image-105543 size-full\" src=\"https:\/\/physicsworld.com\/wp-content\/uploads\/2023\/01\/Upright-rt-featured.jpg\" alt=\"Upright radiotherapy\" width=\"1200\" height=\"676\" srcset=\"https:\/\/physicsworld.com\/wp-content\/uploads\/2023\/01\/Upright-rt-featured.jpg 1200w, https:\/\/physicsworld.com\/wp-content\/uploads\/2023\/01\/Upright-rt-featured-211x119.jpg 211w, https:\/\/physicsworld.com\/wp-content\/uploads\/2023\/01\/Upright-rt-featured-1024x577.jpg 1024w, https:\/\/physicsworld.com\/wp-content\/uploads\/2023\/01\/Upright-rt-featured-317x179.jpg 317w, https:\/\/physicsworld.com\/wp-content\/uploads\/2023\/01\/Upright-rt-featured-768x433.jpg 768w, https:\/\/physicsworld.com\/wp-content\/uploads\/2023\/01\/Upright-rt-featured-710x400.jpg 710w, https:\/\/physicsworld.com\/wp-content\/uploads\/2023\/01\/Upright-rt-featured-732x412.jpg 732w, https:\/\/physicsworld.com\/wp-content\/uploads\/2023\/01\/Upright-rt-featured-720x406.jpg 720w, https:\/\/physicsworld.com\/wp-content\/uploads\/2023\/01\/Upright-rt-featured-635x358.jpg 635w, https:\/\/physicsworld.com\/wp-content\/uploads\/2023\/01\/Upright-rt-featured-350x197.jpg 350w, https:\/\/physicsworld.com\/wp-content\/uploads\/2023\/01\/Upright-rt-featured-257x145.jpg 257w, https:\/\/physicsworld.com\/wp-content\/uploads\/2023\/01\/Upright-rt-featured-300x169.jpg 300w, https:\/\/physicsworld.com\/wp-content\/uploads\/2023\/01\/Upright-rt-featured-160x90.jpg 160w, https:\/\/physicsworld.com\/wp-content\/uploads\/2023\/01\/Upright-rt-featured-128x72.jpg 128w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><\/a><script type=\"application\/json\">\"\\u003Cstrong\\u003EUpright radiotherapy\\u003C\\\/strong\\u003E Leo Cancer Care\\u2019s Eve patient positioning system is installed at Centre L\\u00e9on B\\u00e9rard in Lyon, France. The system uses standard immobilization devices to ensure patient stability and comfort. (Courtesy: Leo Cancer Care)\"<\/script><figcaption class=\"gallery-item__caption\"><strong>Upright radiotherapy<\/strong> Leo Cancer Care\u2019s patient positioning system is installed at Centre L\u00e9on B\u00e9rard in Lyon, France. (Courtesy: Leo Cancer Care)<\/figcaption><\/figure>\n<p>n<\/p>\n<p>Another technology to keep a close eye on is the introduction of upright radiotherapy, pioneered by <a href=\"https:\/\/www.leocancercare.com\/\">Leo Cancer Care<\/a>. Back in January we reported on a <a href=\"https:\/\/physicsworld.com\/a\/patient-positioning-chair-paves-the-way-for-upright-radiotherapy\/\">patient positioning system<\/a> that allows cancer patients to receive radiotherapy whilst sitting upright \u2013 in contrast to having to lie on their back \u2013 a position that should reduce organ movement during treatment and may also be more comfortable for the patient. Since then, several studies have confirmed the benefits of this upright approach for various tumour types, orders have been placed, and the positioning system is now pending 510(k) regulatory clearance for clinical use in the USA.<\/p>\n<p>n<\/p>\n<h3><strong>Wearable wonders<\/strong><\/h3>\n<p>n<\/p>\n<p>Each year we see the emergence of ingenious wearable devices for countless new healthcare monitoring and diagnostic applications; and 2023 was no exception.<\/p>\n<p>n<\/p>\n<figure class=\"size-full\" id=\"attachment_107664\"><a data-featherlight=\"image\" title=\"Click to open image in popup\" href=\"https:\/\/physicsworld.com\/wp-content\/uploads\/2023\/05\/chest-e-tattoo.jpg\"><img decoding=\"async\" loading=\"lazy\" class=\"wp-image-107664 size-full\" src=\"https:\/\/physicsworld.com\/wp-content\/uploads\/2023\/05\/chest-e-tattoo.jpg\" alt=\"Sarnab Bhattcharya and Nanshu Lu from The University of Texas at Austin\" width=\"1200\" height=\"675\" srcset=\"https:\/\/physicsworld.com\/wp-content\/uploads\/2023\/05\/chest-e-tattoo.jpg 1200w, https:\/\/physicsworld.com\/wp-content\/uploads\/2023\/05\/chest-e-tattoo-211x119.jpg 211w, https:\/\/physicsworld.com\/wp-content\/uploads\/2023\/05\/chest-e-tattoo-1024x576.jpg 1024w, https:\/\/physicsworld.com\/wp-content\/uploads\/2023\/05\/chest-e-tattoo-317x178.jpg 317w, https:\/\/physicsworld.com\/wp-content\/uploads\/2023\/05\/chest-e-tattoo-768x432.jpg 768w, https:\/\/physicsworld.com\/wp-content\/uploads\/2023\/05\/chest-e-tattoo-711x400.jpg 711w, https:\/\/physicsworld.com\/wp-content\/uploads\/2023\/05\/chest-e-tattoo-732x412.jpg 732w, https:\/\/physicsworld.com\/wp-content\/uploads\/2023\/05\/chest-e-tattoo-720x405.jpg 720w, https:\/\/physicsworld.com\/wp-content\/uploads\/2023\/05\/chest-e-tattoo-635x357.jpg 635w, https:\/\/physicsworld.com\/wp-content\/uploads\/2023\/05\/chest-e-tattoo-350x197.jpg 350w, https:\/\/physicsworld.com\/wp-content\/uploads\/2023\/05\/chest-e-tattoo-257x145.jpg 257w, https:\/\/physicsworld.com\/wp-content\/uploads\/2023\/05\/chest-e-tattoo-300x169.jpg 300w, https:\/\/physicsworld.com\/wp-content\/uploads\/2023\/05\/chest-e-tattoo-160x90.jpg 160w, https:\/\/physicsworld.com\/wp-content\/uploads\/2023\/05\/chest-e-tattoo-128x72.jpg 128w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><\/a><script type=\"application\/json\">\"\\u003Cstrong\\u003EMobile cardiac monitor\\u003C\\\/strong\\u003E Sarnab Bhattcharya, Nanshu Lu and colleagues are developing an ultrathin and stretchable chest e-tattoo that could detect early signs of heart disease. (Courtesy: The University of Texas at Austin)\"<\/script><figcaption class=\"gallery-item__caption\"><strong>Mobile cardiac monitor<\/strong> Sarnab Bhattcharya, Nanshu Lu and colleagues are developing a chest e-tattoo that could detect early signs of heart disease. (Courtesy: The University of Texas at Austin)<\/figcaption><\/figure>\n<p>n<\/p>\n<p>For starters, a team headed up at The University of Texas at Austin created an ultrathin, stretchable <a href=\"https:\/\/physicsworld.com\/a\/ultrathin-e-tattoo-provides-continuous-heart-monitoring\/\">electronic tattoo that provides continuous cardiac monitoring<\/a>. Attached to the chest via a medical dressing, the e-tattoo could detect early signs of heart disease outside of the clinic. Meanwhile, a <a href=\"https:\/\/physicsworld.com\/a\/wireless-ultrasound-monitor-is-ready-for-a-workout\/\">wearable ultrasound transducer<\/a> developed at the University of California San Diego could be used to monitor patients with serious cardiovascular conditions, as well as to help athletes keep track of their training.<\/p>\n<p>nn<\/p>\n<p>Other novel wearables reported this year include a <a href=\"https:\/\/physicsworld.com\/a\/wearable-ring-measures-intensity-and-frequency-of-scratching\/\">ring device<\/a> that accurately gauges how intensely its wearer is scratching their skin, a <a href=\"https:\/\/physicsworld.com\/a\/miniaturized-ultrasound-scanner-could-help-detect-breast-cancer-earlier\/\">miniaturized ultrasound scanner<\/a> that may provide earlier detection of breast cancer, and <a href=\"https:\/\/physicsworld.com\/a\/earbud-biosensors-provide-continuous-monitoring-of-brain-activity-and-lactate-levels\/\">earbud biosensors<\/a> that continuously and simultaneously measure the electrical activity of the brain and levels of lactate in sweat.<\/p>\n<p>n<\/p>\n<p>Finally, researchers from the Medical University of Vienna designed a <a href=\"https:\/\/physicsworld.com\/a\/wearable-coil-vest-could-change-the-game-in-breast-mri\/\">prototype MRI coil that can be worn like a sports bra<\/a>. The so-called BraCoil is a vest-like receive-only coil array made of flexible coil elements that enables 3 T MR imaging of patients in both supine (lying on their back) and prone (lying on their front) positions. Designed to improve comfort, and reduce preparation and acquisition time, the BraCoil also produced an up to three-fold improvement in signal-to-noise ratio compared with standard coils.<\/p>\n<p>n<\/p>\n<div class=\"box-section\">\n<h2 class=\"box-section__title\"><\/h2>\n<\/p>\n<p>n<\/p>\n<p><strong><a class=\"no-caption size-thumbnail\" href=\"https:\/\/physicsworld.com\/wp-content\/uploads\/2023\/12\/ropp-circle.png\" data-featherlight=\"\"><img decoding=\"async\" loading=\"lazy\" class=\"alignnone size-thumbnail wp-image-111723\" src=\"https:\/\/physicsworld.com\/wp-content\/uploads\/2023\/12\/ropp-circle-317x317.png\" alt=\"Reports on Progress in Physics logo\" width=\"317\" height=\"317\" srcset=\"https:\/\/physicsworld.com\/wp-content\/uploads\/2023\/12\/ropp-circle-317x317.png 317w, https:\/\/physicsworld.com\/wp-content\/uploads\/2023\/12\/ropp-circle-211x211.png 211w, https:\/\/physicsworld.com\/wp-content\/uploads\/2023\/12\/ropp-circle-1022x1024.png 1022w, https:\/\/physicsworld.com\/wp-content\/uploads\/2023\/12\/ropp-circle-768x769.png 768w, https:\/\/physicsworld.com\/wp-content\/uploads\/2023\/12\/ropp-circle-399x400.png 399w, https:\/\/physicsworld.com\/wp-content\/uploads\/2023\/12\/ropp-circle-411x412.png 411w, https:\/\/physicsworld.com\/wp-content\/uploads\/2023\/12\/ropp-circle-409x410.png 409w, https:\/\/physicsworld.com\/wp-content\/uploads\/2023\/12\/ropp-circle-635x636.png 635w, https:\/\/physicsworld.com\/wp-content\/uploads\/2023\/12\/ropp-circle-197x197.png 197w, https:\/\/physicsworld.com\/wp-content\/uploads\/2023\/12\/ropp-circle-193x193.png 193w, https:\/\/physicsworld.com\/wp-content\/uploads\/2023\/12\/ropp-circle-250x250.png 250w, https:\/\/physicsworld.com\/wp-content\/uploads\/2023\/12\/ropp-circle-90x90.png 90w, https:\/\/physicsworld.com\/wp-content\/uploads\/2023\/12\/ropp-circle-128x128.png 128w, https:\/\/physicsworld.com\/wp-content\/uploads\/2023\/12\/ropp-circle-24x24.png 24w, https:\/\/physicsworld.com\/wp-content\/uploads\/2023\/12\/ropp-circle-48x48.png 48w, https:\/\/physicsworld.com\/wp-content\/uploads\/2023\/12\/ropp-circle-96x96.png 96w, https:\/\/physicsworld.com\/wp-content\/uploads\/2023\/12\/ropp-circle-150x150.png 150w, https:\/\/physicsworld.com\/wp-content\/uploads\/2023\/12\/ropp-circle-300x300.png 300w, https:\/\/physicsworld.com\/wp-content\/uploads\/2023\/12\/ropp-circle.png 1062w\" sizes=\"auto, (max-width: 317px) 100vw, 317px\" \/><\/a><\/strong><\/p>\n<p>n<\/p>\n<p><em>Physics World<\/em>&#8216;s coverage of the Breakthrough of the Year is supported by <em><a href=\"https:\/\/iopscience.iop.org\/journal\/0034-4885\">Reports on Progress in Physics<\/a><\/em>,\u00a0which offers unparalleled visibility for your ground-breaking research.<\/p>\n<p>n<\/p>\n<p>&nbsp;<\/p>\n<p>n<\/p>\n<p>&nbsp;<\/p>\n<p>n<\/p>\n<p>n<\/p><\/div>\n<p>n<\/p>\n<p>The post <a rel=\"nofollow\" href=\"https:\/\/physicsworld.com\/a\/medical-physics-and-biotechnology-highlights-of-2023\/\">Medical physics and biotechnology: highlights of 2023<\/a> appeared first on <a rel=\"nofollow\" href=\"https:\/\/physicsworld.com\">Physics World<\/a>.<\/p>\n<p>n<\/p>\n","protected":false},"excerpt":{"rendered":"<p>This year, the Physics World team selected a medical innovation as the Breakthrough of the Year: the development of a digital bridge that restores communication between the brain and spinal cord, enabling a man with paralysis to stand and walk naturally. We also reported on several other neural engineering advances, including a neuroprosthesis that restores&hellip; <a class=\"more-link\" href=\"https:\/\/hadamard.com\/c\/medical-physics-and-biotechnology-highlights-of-2023\/\">Continue reading <span class=\"screen-reader-text\">Medical physics and biotechnology: highlights of 2023<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[1],"tags":[],"class_list":["post-38","post","type-post","status-publish","format-standard","hentry","category-allgemein","entry"],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/hadamard.com\/c\/wp-json\/wp\/v2\/posts\/38","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/hadamard.com\/c\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/hadamard.com\/c\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/hadamard.com\/c\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/hadamard.com\/c\/wp-json\/wp\/v2\/comments?post=38"}],"version-history":[{"count":0,"href":"https:\/\/hadamard.com\/c\/wp-json\/wp\/v2\/posts\/38\/revisions"}],"wp:attachment":[{"href":"https:\/\/hadamard.com\/c\/wp-json\/wp\/v2\/media?parent=38"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/hadamard.com\/c\/wp-json\/wp\/v2\/categories?post=38"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/hadamard.com\/c\/wp-json\/wp\/v2\/tags?post=38"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}